I love the new Spaces feature in Leopard, aka Apple OS 10.5.
1) Lotus Notes
2) VMWare Fusion
4) Apple Mail, Safari and iChat
I’ve gotten pretty quick with using the keyboard shortcuts to jump around screen.
[Update: I stopped using Spaces while at work, it became more of a pain to remember which window had what folder view open and having to move back and forth. I might revisit this in the future with a more concrete plan for each space]